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Research Article - Asian Journal of Biomedical and Pharmaceutical Sciences (2017) Volume 7, Issue 60
Tinospora cordifolia an Augmenting Agent for Quality of Life in Cancer: an Overview
Surgery, chemotherapy and radiotherapy are major approach of cancer treatment and excess reactive oxygen species molecule is generated during chemotherapy. Furthermore, chemotherapy depresses the immunity inviting infection with altered cognitive function. T. cordifolia having free radical scavenging capacity, decreases oxidative stress by increasing glutathione & other anti-oxidant enzyme and down regulate the pro-inflammatory cytokines. It stimulates helper T cellular immune, innate immune response and develops antigen specific immunity also increase the acetylcholine which is responsible for enhancing the cognitive function. Additionally, it inhibits cell proliferation, differentiation and induced apoptosis that prevent anti-tumor activity. Thus, we can assume that impaired quality of life due to chemotherapy in cancer will be well-adjusted by T. cordifolia and also have anti-tumor activity.
Author(s): Kapil Yadav