The thyroid dysfunction is one of the most common endocrine disorders. Sikkim lies in the severely iodine deficient zone. This was a hospital based cross-sectional study. The serum samples were used to check the levels of thyroid stimulating hormone (TSH), triiodothyronine (T3) and thyroxine (T4). Out of 674 patients with suspected thyroid dysfunction, 83% were Euthyroid followed by 10 % of patients having subclinical hypothyroidism. The incidence subclinical hyperthyroidism (1%) were lowest. Females were found to be maximum with thyroid disorders. The datas were represented as percentage and mean ± SD. Thyroid hormones were compared among the different thyroid disorder by One way analysis of variance (ANOVA). High incidence of thyroid dysfunction in females with subclinical hypothyroidism indicates that it still exists as a public health problem in Sikkim regardless of the implementation of iodized salt program since the last decade.