Asian Journal of Biomedical and Pharmaceutical Sciences

- Asian Journal of Biomedical and Pharmaceutical Sciences (2014) Volume 4, Issue 32

Studies on in vitro antioxidant potential of pod and seed parts of Bauhinia malabarica Roxb

Aim: In Indian traditional medicine, importance of Bauhinia species is well evidenced from earlier literature. In the present investigation, the antioxidant and free radical scavenging efficiencies of 70% acetone and 50% methanol extracts of Bauhinia malabarica pod and seed were examined.
Materials and Methods: The extracts were screened for different antioxidant assays such as reducing power, DPPH?, nitric oxide, hydroxyl radical scavenging, metal chelating, ABTS?+ scavenging activity, lipid peroxidation preventive property and anti-haemolytic activities.
Results: It contribute significantly to the total antioxidant activity of the test drug. In β - carotene-linoleic acid system all the extracts, exhibited good antioxidant activity and the values were comparably higher than the synthetic antioxidant, BHT and BHA. Among the samples analyzed acetone extract of B. malabarica seed determined significant (p<0.05) antioxidant activity in terms of reducing power, DPPH•, metal chelating and ABTS•+ activity.
Conclusion: On the basis of the results obtained, seeds of B. malabarica were found to be a potent source of natural antioxidants due to their marked antioxidant activity. Overall, the acetone was found to be the best solvent for the extraction of antioxidant compounds. The results presented here implies that the consumption of such a legume food would not only improve the nutrient utilization but also provide the potential source of nutraceuticals for human health.

Author(s): Thenmozhi K, Karthika K, Manian S, Paulsamy S

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