Malignant tumors involving maxilla is rather rare. This comprises about 1% of all malignant tumors seen in humans. This tumor constitutes roughly 3% of all head and neck malignancies. This article discusses our experience in managing patients with malignant tumors of maxilla. All our patients underwent total maxillectomy followed by post operative irradiation. Mean survival rates of our patients ranged from 2.5 years to 3 years. Survival rates were also dependent on the histology of the tumor. This is a retrospective study of patients who presented to our Institution between 2006-2010. In our study we found that surgery had a definitive role despite the staging. Even advanced cases had a definite improvement in the quality of life. All our patients received post operative irradiation (full course) following total maxillectomy.