Present communication is based on extensive ethnobotanical studies done during 2009 to 2012 in the Ahmednagar district of Maharashtra. Ahmednagar is a place of attraction to many herbal drug practitioners and dealers of the neighbouring areas. Akole taluka forests of the district are especially rich in medicinal plants and exhibit remarkable plant diversity. The tribals residing the forests use plants for treating different ailments. Total 12 tribes inhabit the district, of these Bhil, Mahadeo koli, Pardhi, Thakar are the major tribes in the district. During the study total 66 plant species belongs to 38 families used for medicinal purposes have been documented. Enumeration includes details like name of the disease, plant part used, method of preparation of medicine, doses, mode of administration, etc.