Asian Journal of Biomedical and Pharmaceutical Sciences

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Formulation and Characterization of Kaempferol Nanoparticles

Nanoparticles of Kaempferol were prepared using varying polymer drug ratio with PLGA (50:50) as the polymer, using solvent displacement method. The prepared nanoparticles were screened for the various studies like size and shape determination using light scattering and SEM. The in-vitro antioxidant profiles of the prepared nanoparticles were studied and compared with free Kaempferol using DPPH method. The nanoparticles of uniform size were prepared, the % EE of 20:1 polymer drug ratio was found to be maximum and the free radical scavenging activity of Kaempferol trapped in nanoparticles was even increased when compared with its free form.

Author(s): Kuldeep G, Eisha G