Background: Disinfectant failure could increase microbial load on fomites and predispose patients to nosocomial infection. The aim of this study was to evaluate the efficacy of disinfectants using standard methods in hospitals in Kogi State. Materials and methods: Dettol and Izal which are phenolic disinfectants were evaluated for efficacy against phenol using locally isolated multidrug resistant Pseudomonas aeruginosa as test organism in randomly selected hospitals in Kogi state between November 2011 to June 2012 Standard method of Rideal-Walker, Chick-Martin and capacity test of Kelsey-Sykes were used. Results: The Rideal-Walker coefficient for izal and Dettol were 2.5 and 3 respectively while Chick-Martin coefficient for izal and dettol were 2 and 2 respectively. Capacity test of Kelsey-Sykes also showed satisfactory results at first 2 concentrations used for both disinfectants. Conclusion: The disinfectants tested were considered effective for use in the health care facilities.