International Journal of Pure and Applied Zoology

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Deltamethrin Induced Alteration in Na+-K+, Mg2+, Ca2+ Associated Atpases Activity in The Freshwater Fish Cirrhinus Mrigala

Deltamethrin is a synthetic pyrethroid, contaminating aquatic ecosystems as a potential toxic pollutant; it affects the physiological function of the aquatic fauna. In this present study, the impact of exposure of the freshwater fish Cirrhinus mrigala to both lethal and sub lethal concentrations (8 μl/L and 0.8 μl/L) of deltamethrin on the activities of Na+-K+ATPase, Ca2+ and Mg2+ associated ATPases in gills, muscle and liver was assessed. As a result significant (p<0.05) decrease was found in Na+-K+, Ca2+ and Mg2+ ATPase activities of the fish. The present studies conclude that the deltamethrin alters the membrane permeability of ATPases, resulting in the breakdown of the active transport mechanism and causes the alterations in physiology of whole organisms.

Author(s): M. David, J. Sangeetha, E.R. Harish, J. Shrinivas and V.R. Naik