Background: The present study was conducted to find out whether the Valsalva test and thus the autonomic nervous system are affected in patients of severe iron deficiency anemia.
Materials and methods: In this study the change in heart rate was recorded with the help of ECG machine during and after the valsalva maneuver. The change in heart rate was compared between 60 patients of severe iron deficiency anemia and 60 ages and socioeconomically matched normal subjects.
Result: It was found that the change in heart rate was significantly altered in patients of severe iron deficiency anemia (p<0.0001) when compared to controls.
Conclusion: The present study demonstrates an altered autonomic balance in patients with true iron deficiency anemia.