International Journal of Pure and Applied Zoology

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Antibiotic Susceptibility of Bacterial Strains Isolated from Patients with Respiratory Tract Infections

This study was aimed to observe the susceptibility pattern of bacterial isolates from respiratory tract infection (RTI). The study was carried out between June, 2012 and December, 2012. Sputum and throat swab specimens were collected aseptically from patients and cultured on the appropriate bacteriological media. Bacterial isolates were identified by biochemical tests and antimicrobial susceptibility performed by standard methods. Out of 360 specimens, some 337 (93.6%) species of various bacteria isolated. The prevalence of bacteria spp. isolated were as follows Streptococcus pneumoniae (36%), Klebsiella pneumoniae (28.4%), Staphylococcus aureus (24%), Pseudomonas aeruginosa (11%) and Escherichia coli (0.6%). The susceptibility patterns varied from one bacterial isolates to the other depending on the drug. The susceptibility test against microbial isolates of 13 commercially used antibiotics was used. Most of the isolates were susceptible to Amikacin, Cefotaxime, Ofloxacin, Netilmycin, Ciprofloxacin and Ceftriazone. 50 % of the bacterial spp. was resistant to the other antibiotics. Most of the bacteria were shown 92.6% sensitivity to Amikacin. Pseudomonas aeruginosa was 99% resistant to ampicillin, amoxicillin, 98% resistant to roxithromycin, 96% resistant to sparfloxacin and cefuroxime. These findings have clinical and epidemiological significance

Author(s): C. MANIKANDAN AND A. AMSATH