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Angiolymphoid Hyperplasia

Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon benign idiopathic condition that manifests in adults, characterized by isolated or grouped papules, plaques, or nodules in the skin of the head and neck. Most patients present with lesions in the periauricular region, scalp or forehead. The other rare sites of involvement include the hands, shoulders, breasts, penis, oral mucosa, orbit and scrotum. It is a distinct histopathologic entity, marked by a proliferation of blood vessels with distinctive large endothelial cells, accompanied by a characteristic inflammatory infiltrate that includes eosinophils. Though a few cases of nephropathy have been reported in patients with ALHE there is no strong association. This is in contrast to the related entity, Kimura disease, for which the association with nephrotic syndrome is strong. We present a rare occurance of ALH in a 35 year old post renal transplant male patient which has not been reported so far.

Author(s): Ramesh Aravamuthan A Mani Suryakumar Sarankumar s