Myoepithelial carcinoma is a rare malignant epithelial neoplasm composed of variable proportions of salivary gland tumor. Most of cases which have been reported in the literature were located in salivary glands, except for a few cases occurring in unusual locations such as breast, lacrimal gland, nose, paranasal sinus, trachea, bronchus, and lung. We report a case 59-year-old female manifesting as nasal obstruction with left recurrent epistaxis and on nasal endoscopic examination was found to have a polypoid tumor in the left nasal cavity. The CT scan demonstrated a soft tissue mass without extension to the nasopharynx or bony destruction. The tumor was surgically treated with endoscopic excision successfully from the left nasal septum. Histopathologic examination revealed the tumor to consist of a mixture of a solid, tubular structures. Based on the histological and immunohistochemical findings, the tumor was diagnosed to be an myoepithelial carcinoma. The patient has had neither recurrence nor metastasis 8 months postoperatively The purpose of this study was to describe myoepithelial carcinoma with nasal location, which is exceptionally reported in the literature.