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Journal of Materials Science and Nanotechnology | Volume: 2
August 20-21, 2018 | Paris, France
Materials Science and Materials Chemistry
International Conference on
Forsterite porous nanoceramics as a novelty in medical applications
Alexandra Avram, Adriana Marieta Naghiu, Maria Gorea
and
Maria Tomoaia-Cotisel
Babes-Bolyai University of Cluj-Napoca, Romania
T
he main purpose of this study is to develop novel
nanoceramics based on forsterite (F) with high bioactivity
and enhanced mechanical properties for medical applications.
Forsterite nanoceramics were obtained by two methods
using solid state (FS) and sol-gel (SG) synthesis. Their powders
were pressed into pellets and thermally treated at different
temperatures, 1200°C, 1300°C, and 1400°C. The compactness
characteristics of the obtained forsterite ceramics were
determined. The median apparent porosity of FS ceramics falls
in the range of 17-46%, while that for SG ceramics is of 27-39%.
With the increase in temperature, the apparent porosity of FS
ceramics decreases comparatively to that of SG ceramics. In
vitro bioactivity testing was performed by immersing the FS and
SG ceramic pellets into simulated body fluid (SBF) for 1 week to
several months. The formation of hydroxyapatite on the surface
and within the pores of FS and SG-derived forsterite ceramics is
confirmed even after 1 week, by X-ray diffractions (XRD). After
3 months of immersion in SBF, the surface of forsterite ceramic
is covered by an organized fibrous network of hydroxyapatite
elongated crystals. This fibrous hydroxyapatite was evidenced
by atomic force microscopy (AFM). Mechanical characteristics
were also determined, both by compression, flexural strength
and Young modulus by nanoindentation. FS ceramics showed
a median flexural strength of about 24 MPa, about 4 times
higher than that of SG ceramics (6MPa). The value of the Young
modulus determined through nanoindentation falls in the
range of 40 to 50 MPa for SG ceramics, and between 87 to 101
MPa, for FS ceramics. The novelty element of this investigation
is also represented by the use of forsterite at nanometric scale,
as porous nanomaterials with improved mechanical properties
for bone grafts, as coatings for innovativemetallic implants, and
as drug delivery systems for orthopaedic medical applications.
Speaker Biography
Alexandra Avram is an Ph.D. candidate and a research assistant at the Physical Chemistry
Center, Faculty of Chemistry and Chemical Engineering, Babe-Bolyai University. Her
research interests include nanomaterials, biomaterials for bone tissue engineering (glass,
ceramics, and composites) and drug delivery.
e:
avram.v.alexandra@gmail.com