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Virology Research Journal
|
Volume 2
Page 46
allied
academies
IMMUNOLOGY AND CELL BIOLOGY
BACTERIOLOGY AND INFECTIOUS DISEASES
&
Global Summit on
Global Congress on
J u n e 2 5 - 2 6 , 2 0 1 8 | A m s t e r d a m , N e t h e r l a n d s
Joint Event on
THE NEW DOCTRINE OF ACUTE PNEUMONIA AND THE FIRST RESULTS OF
PATHOGENETIC APPROACHES TO TREATMENT
Igor Klepikov
Tel Aviv Sourasky Medical Center, Russia
T
reatment of acute pneumonia (АР) in recent decades focused solely on antibiotic therapy,does not include pathogenetic,
specific methods of assistance and repeats the principles of treatment of other inflammatory diseases. Reducing the
effectiveness of antimicrobial drugs,the emergence and the increasing number of antibiotic-resistant pathogens and a gradual
increase in the frequency of purulent complications attach importance and urgency to the solution of this problem. The first step
in this decision is a revision of ideas about the nature and mechanisms of АP. This work has been done and tested in a clinical
setting in the years 1976-1984 in Novokuznetsk State Institute for postgraduate doctors (USSR, Russia). The basis of the new
doctrine АP was based on the following scientific medical axioms, already having previous scientific justification: The body’s
response to any stimulus, including the initiation of inflammation, is highly individual and unique; the basis for the inflammatory
transformation of the body tissue is a vascular reaction with a specific stage sequence; small and big circles of blood circulation
not only have a direct relationship, but an inverse relationship; among the nonspecific forms of inflammation, AP is the only
process occurring in the system of lesser circulation and the same medical procedure can have different effects on inflammation
in the small or big circles of blood circulation. Following private studies were additionally performed: Experimental model of
AP(4 series of experiments, 44 animals) obtaining a model of pleural complications; X-ray examination 56 lung anatomical
preparations with different forms of the AP, taken from the dead patients; record comparative rheopulmonography before and
after performing medical procedures (36 patients) and analysis of the observation and treatment of 994 children with AP and its
various destructive and pleural complications. The revised treatment guidelines were applied in 101 patients in the initial period
of aggressive forms of АP. The received results allow to speak about possibility of the guaranteed prevention of suppurative and
destructive complications of the disease.
igor.klepikov@yahoo.comVirol Res J 2018, Volume 2