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Journal of Timely Topics in Clinical Immunology | Volume 2
allied
academies
July 26-28, 2018 | Moscow, Russia Immunology
11th Annual Congress on
For stable forms of vitiligo, many are the surgical techniques
proposed, in order to improve patients’ response to NB
UVB. The surgical techniques for the treatment of vitiligo can
be classified according to the nature of the graft. Some surgical
techniques are:
• Minigrafts.
• Suction Blister, in which the top of the blister induced by
suction is used as grafts.
• Split Thickness Grafts inwhich a sheet of skin of 0,2-0,3mm
thickness, thus consisting almost exclusively of epidermis is
used as a graft.
• Needling, in which, with a needle it is be possible
transplantating pigment cells from the edge to the center
of the leukoderma area. After, the patients are submitted
to phototherapy NB UVB.
However, patients submitted to needling have different
degrees of repigmentation. We wondered why and supposed
that when transplantating cells from the edge compared with
when transplantating cells at least 3 cm further, better results
could be achieved in the second case. Considering vitiligo as an
auto immune disease, we supposed that cells far from the edge
could be in better immunologic conditions, comparing to those
near the edge, where the number of auto Antibodies could be
higher. In order to put this hypothesis to the test, we have done
needling in both sides of the same patient. We have chosen one
patient who had vitiligo lesions on both sides of the body. On
the right side of the body, the donor cells were near the edge
of the lesions. On the left side of the body, the donor cells were
atleast 3cm far from the edge.
Speaker Biography
Patricia Fabrini has her expertise in Phototherapy, area in which she has been working
for seventeen years. The major issues of her study arevitiligo, psoriasis and mycosis
fungoides. And invitiligo, she has developed theories about the varies responses to
surgical treatments of vitiligo, which could improve NB-UVB response.
e:
Patricia Fabrini1
Marco Araujo1 and Wander Valentim 2
1Santhè Clinic , Brazil
2Medical School-UFMG, Brazil
Evaluation of possible Immunological variants influencing the clinical response to
needling – A new approach in the treatment of Vitiligo