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Research and Reports in Gynecology and Obstetrics | Volume 3
November 14-15, 2019 | Singapore
Obstetrics and Gynecology
4th International Conference on
HEV induced encephalopathy during pregnancy- Life threatening condition
Kamrun Nessa and Khaled Kaisar
BRB Hospital LTD, Bangladesh
Hepatitis E virus infection has been a major concern in
the pregnant women due to its fulminant nature in
pregnancy. It increases mortality and morbidity in pregnant
females as compared to the non-pregnant females and
males. The study was performed to evaluate the maternal
and fetal outcome in pregnancy with hepatic encephalopathy
due to HEV infection. All pregnant HEV Positive patients with
signs and symptoms of encephalopathy admitted in the ICU
of BRB Hospital ltd during the period of January 2018 and
August 2018 were included in this study. Maternal outcome
in terms of acute Hepatic failure, coagulation failure, hepatic
encephalopathy and maternal mortality was studied. Fetal
outcome in terms of preterm labor, intrauterine fetal death,
live birth was studied. In this study we found that pregnant
women with HEV infection having hepatic encephalopathy
had a maternal mortality rate was 16 %. Maternal death is
mostly due to the coagulation failure. The most common
obstetric complication was IUFD (25%) and preterm labor
(16%). Continuation of pregnancy rate was 58%. There was
no PPH as patients were treated by Fresh Frozen Plasma
and keeping Prothrombin Time below 17 prior induction
Prophylactic intrauterine condom catheter was given in every
patient after delivery. Conclusions: Mortality is high among
HEV with encephalopathy. But we can reduce mortality
and morbidity by using FFP and reducing serum ammonia
aggressively.
Speaker Biography
Kamrun Nessa graduated with a MBBS degree from Jahurul Islam
Medical College under Dhaka University, Bangladesh in May 1999. She
there on went obtaining MCPS from BCPS, Bangladesh in January 2006
and FCPS from BCPS, Bangladesh in January 2007. She worked as an
Assistant Professor at EmamMedical College & Hospital, India fromMay
2008 to October 2011 and promoted as Associate Professor at the same
college from November 2011 to January 2018. She further obtained her
fellowship on minimal access surgery fromWorld Laparoscopy Hospital,
India, 2018 and fellowship on ART from India in 2018. She is currently
working as a consultant at department of Obstetrics and Gynecology,
BRB Hospital Ltd, Bangladesh.
e:
Kamrun Nessa et al., Res Rep Gynaecol Obstet, Volume:3
DOI: 10.35841/2591-7366-C3-008