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Journal of Materials Science and Nanotechnology | Volume: 2
August 20-21, 2018 | Paris, France
Materials Science and Materials Chemistry
International Conference on
In Vivo Dosimetry in Total Body Irradiation
Eilen Llanes veiga, Rodolfo Alfonso Laguardia
and
Roberto Caballero Pinelo
Institute of Oncology and Radiobiology, Cuba
T
otal Body Irradiation (TBI) is a radiotherapy technique
that consists of irradiating homogeneously the whole
patient’s body and it is characterized by an extended source
to surface distances and the use of large irradiation fields.
The limitations of the available input data and inherent
problems with the calculation procedures make it very
difficult to accurately determine the dose distributions in TBI.
For these reasons, it is highly recommended to use In Vivo
Dosimetry (IVD), to guarantee the quality of TBI treatments
as a direct measurement of the delivered dose. An IVD QA
system was implemented based on semiconductor diodes
and radiochromic films. For the commissioning of the
system, both detector types were calibrated independently.
This guarantees the traceability of the measurements. An
assessment was made on the sources of uncertainties. A
tolerance level of ±10% was established for the combined
contribute on of both computational and experimental
uncertainties. An experiment to a phantomwas carried out to
simulate a clinical TBI procedure. In this way, the calibration
of the dosimetry system was corroborated. Finally, the
IVD system was applied in TBI of three real patients. The
discrepanciesobtainedbetweentheprescribedandmeasured
doses were below the established tolerance level of ±10 %.
e:
ellanes2307@gmail.com