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April 15-16, 2019 | Milan, Italy
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
GlobalWomen Health 2019 Research and Reports in Gynecology and Obstetrics | ISSN: 2591-7366 | Volume 3
BREAST CANCER,
GYNECOLOGY ANDWOMEN HEALTH
2nd World Congress on
WOMEN HEALTH AT HIGH ALTITUDE: PHYSIOLOGY AND REPRODUCTIVE PER-
SPECTIVES
Dishari Ghosh1, Snigdha Shaw1, Niroj Sethy1, Ekta Kohli1, G Bhaumik1, P K Reddy1, H BMohanty2 and
Bhuvnesh Kumar 1
1 Defence Institute of Physiology and Allied Sciences, India
2 Ministry of Home Affairs- ITBP, India
In the current scenario, there is a rise in number of women being commissioned into the forces and they
constitute a significant proportion of the active, reserve and allied component of Indian military and border
security forces. They are often deployed at high altitude areas, as a part of their duties and there is paucity of
information on the effect of hypoxic exposure on women health particularly their physiology and reproductive
functions. High altitude hypoxia triggers a series of systemic adjustments to maintain an adequate oxygen-
ation of the different organs termed as acclimatization. The physiological adjustment of women to altitude is
comparatively less explored until recently. There are a few reports and studies on the hypoxia and physiological
responses of women to high altitude stress but remain contentious. This presentation is to focus on physi-
ological and reproductive function of women at high altitude with the aim whether women demonstrated
similar physiological adjustments to those previously found in men and the extent to which these responses
are attributed to the circulating ovarian or gonadal hormones and whether native women at high-altitude and
sea level residents behave differently and are at increased risk for acute altitude sickness. We have carried out
extensive field trials at sea level as well as among native women at high altitude, Leh (11,700ft). Different phys-
iological parameters like, blood pressure, heart rate, SpO2, heart rate variability, were measured along with
recording of menstrual diary and blood sampling for hormonal assays. We found average age of menarche was
much higher whereas average age of menopause was found lower compare to sea level. Late onset of men-
arche with low ovarian reserve may trigger early menopause with altered hormonal level. Present study will
help to provide a data base on valuable information about the physiological response and how intense hypoxia
impinges the reproductive health of Indian women at high altitude however, the hidden reason behind these
variations should be enlightened to understand the actual role of hypoxia.
Res Rep Gynaecol Obstet 2019, Volume 3 | DOI: 10.4066/2591-7366-C2-006