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Page 32

allied

academies

Microbiology: Current Research

Volume 2

International Conference on

Emerging Diseases, Outbreaks & Case Studies

&

16

th

Annual Meeting on

March 28-29, 2018 | Orlando, USA

Influenza

M

olecular typing of 964 specimens from patients in

Ethiopia with lymph node or pulmonary tuberculosis

showed a similar distribution of

Mycobacterium tuberculosis

strains between the two disease manifestations and a

minimal role for

M. bovis

. We report a novel phylogenetic

lineage of

M. tuberculosis

strongly associated with the Horn

of Africa. Ethiopia is among the countries with the highest

incidence of tuberculosis (TB) and has a yearly incidence of

261 cases/100,000 population. TB lymphadenitis in cervical

lymph nodes (TBLN) accounts for ≈33% of all new cases in this

country, which is greater than the global average of ≈15%.

Ethiopia has the largest livestock population in Africa (≈51

million cattle), and recent studies have shown that bovine TB

is endemic in this country (estimated prevalence 1%–10%).

To explore the public health risk for bovine TB in Ethiopia, we

have used molecular typing to characterize mycobacterial

isolates from persons with TBLN and pulmonary TB who

were visiting hospitals throughout the country. Our aim was

to define the role of

Mycobacterium bovis

in human TB and

to define the overall structure of the

M. tuberculosis

complex

in Ethiopia.

e:

kmengie@yahoo.com

Mycobacterial lineages causing pulmonary and extra pulmonary tuberculosis, Ethiopia

Teklu Kiros Woldegebriel

Yang-Ming University, Taiwan