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allied
academies
Joint Event on
S e p t e m b e r 1 0 - 1 1 , 2 0 1 8 | D u b l i n , I r e l a n d
TOXICOLOGY AND PHARMACOLOGY
PHARMACEUTICAL CHEMISTRY & DRUG DISCOVERY
&
Global Congress on
International Conference on
Pharma Chem Congress 2018 & Toxicology Congress 2018
Asian Journal of Biomedical and Pharmaceutical Sciences
|
Volume 8
Dina A Shokry, Asian J Biomed Pharmaceut Sci 2018, Volume 8 | DOI: 10.4066/2249-622X-C2-005
PATTERN OF PEDIATRIC POISONING IN
EGYPT- CASES ADMITTED TO NATIONAL
POISONING CONTROL CENTER
Dina A Shokry
Cairo University, Egypt
Background:
Poisoning is an important emergency as well as major problem
in pediatric age groups throughout the world. Most of the poisoning in children
is accidental. Unfortunately, the incidence of deliberate poisoning among
adolescents is increasing due to changing familial and social conditions in
our society.
Aim:
The purpose of this study was to identify the common manner of toxicity
and rate of child toxicity in Egypt. Also, it aimed to elucidate the precipitating
factors for child poisoning and the common complication.
Methods:
The current study was conducted on 500 of Egyptian participant
of both sex in age blew 18 years old at NECTR; participants were classified
into four age groups; toddlers (1-<3 years), early childhood (3-<9 years), late
childhood (9-<13 years) and adolescent (13-<18 years). Data were analyzed
with respect to demographic data, toxicity data: manner of toxicity, type of
poison, its availability to the child, place of exposure, amount and form of
poison, duration between exposure and presentation, the first aid that may be
done to the patient, associated morbidity, history of medications and severity
and mortality rate of each poisons detected by poison severity scoring(PSS)
and the acute physiology and chronic health evaluation (APACHE II).
Results:
Accidental toxicity (58.6%) is still common than intentional toxicity
(41.4%), toddlers were the most common age group in accidental, while
negligence was the most probable cause of accidental toxicity. On other
hand adolescent and females were common age group in suicidal, and family
problems were the most probable cause of suicidal toxicity. There were
multiple significant relations between demographic data (age, sex, residence,
level of education and family status) and type of poison, its availability,
location of exposure, most probable cause of exposure, manner of toxicity.
There were significant relations between PSS and type and amount of poison,
vital signs and CNS manifestations, period of admission and hours of delay.
There were significant relations and positive correlation between APACHE II
and type and amount of poison, vital signs and CNS manifestations, period of
admission and hours of delay.
Conclusion & Recommendations:
The present study proved that accidental
toxicity is still common manner among pediatric age group but there is
increasing in incidence of suicidal toxicity among them. Further attention
from parent is needed and proper care to children in different age group to
prevent and reduce the toxicity in pediatric age group.
Dina A Shokry has completed her bachelor’s degree
in Pharmacy in 2009 from Ain Shams University.
She completed her master’s degree in Analytical
Chemistry from Cairo University in 2013. Currently,
she is pursuing her PhD as a member of Dr Waters
group for finding alternatives to animal testing at
Huddersfield University. She worked as a Teaching
Assistant then as an Assistant Lecturer of Analytical
Chemistry at Future University. She produced high
quality research that was published in several reputed
peer reviewed journals. She has presented her work in
nine conferences. Her work is focused on developing
models for prediction of human intestinal absorption
through
in vitro-in vivo
correlation studies, which has
economic impact in the pharmaceutical industry
field. She developed prediction models from MLC,
solubilization and permeation studies where the
obtained
in vitro
data correlated well with the
in vivo
absorption data and resulted in two recently published
papers.
dinashokry_2004@hotmail.comBIOGRAPHY