Biomedical Research

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Value of magnetic resonance cholangiopancreatography combined with dynamic contrast enhanced CT in differential diagnosis of benign and malignant biliary stricture

Objective: To explore the value of Magnetic Resonance Cholangiopancreatography (MRCP) combined with Dynamic Contrast Enhanced CT (DCE-CT) in differential diagnosis of benign and malignant biliary stricture.

Methods: From Dec 2015-2016, 70 patients suffering biliary stricture were collected in our hospital to receive either conventional X-ray or magnetic resonance cholangiopancreatography combined with enhanced CT examination. With the gold standard of pathological and histological examination, effect and value of those two methods in the diagnosis of benign and malignant biliary stricture were estimated and compared.

Results: The combination of MRCP and DCE-CT is more sensitive and accurate than conventional Xray examination in the diagnosis of benign and malignant biliary stricture. Stenosis length, wall thickness and CT difference in arterial phase, portal venous phase and delayed phase of patients with malignant biliary stricture were significantly higher than those of the patients with benign biliary stricture (P<0.05).

Conclusion: The application of MRCP combined with DCE-CT has significant effect in the differential diagnosis of benign and malignant biliary stricture.

Author(s): Yuhong Wang, Yanhui Wang, Tao Yang, Yueqin Chen