Research Article - Otolaryngology Online Journal (2016) Volume 6, Issue 4
The Relationship Between Nasal Polyps, Mean Platelet Volume, Neutrophile/Lymphocyte Ratio and Platelet Count
Introduction: Nasal polyps, characterized by chronic mucosal inflammation of the nose and paranasal sinuses, are one of the most common reasons of chronic nasal congestion. Objective: This study investigated the relationship of nasal polyps with MPV (mean platelet volume) and NLR (neutrophile to lymphocyte ratio).
Methods: 112 patients and 42 controls were included in this study. Group 1 consisted of males only, Group 2 consisted of females only and Group 3 consisted of both sexes. In all groups, WBC (white blood cell count), RBC (red blood cell count), rdw (red cell distribution width), platelet count, MPV, pdw (platelet distribution width) and NLR parameters from CBC (complete blood count) were compared between patients and controls.
Results and Conclusion: For the Group 1; platelet count (p<0.016) and MPV (p<0.041) parameters were significantly different between patients and controls.WBC and MPV were higher in nasal polyp patients, whereas platelet count was higher in controls. In Group 2; platelet count (p<0.033) and NLR (p<0.030) were significantly lower in patients than the control group. In group 3; platelet count (p<0.001) and NLR (p<0.003) were significantly lower in patients than the control group, whereas MPV (p<0.026) was significantly higher in patients.
conclusion: Platelet count and NLR were significantly lower in patients than the controls, whereas MPV was significantly higher in nasal polyp patients.Author(s): Ferit Akil, Umur Yollu, Fatih Turgut and Muhammed Ayral