Biomedical Research

Research Article - Biomedical Research (2018) Volume 29, Issue 5

Resveratrol significantly inhibits the occurrence and development of cervical cancer by regulating PLSCR1

Cervical cancer is currently the most common female malignancies, and resveratrol is a polyphenol isolated from the skins of grapes that has been reported to significantly alter the cellular physiology of tumor cells, as well as block the process of initiation and progression. Little is known about the role of PLSCR1 in the occurrence and development of cervical cancer. Here, we demonstrated that resveratrol significantly inhibited both the growth of HeLa cells and expression of PLSCR1, which can be recovered by gain of function of PLSCR1. These results suggest that resveratrol mediated cell growth inhibition can be regulated by PLSCR1.

Author(s): Yang Qiu, Xiaoyu Wang

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