Journal of Orthopedic Surgery and Rehabilitation

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Palmar fasciectomy after collagenase Clostridium histolyticum injection for Dupuytrens contracture: A case report.

We present a case of successful salvage fasciectomy after initial collagenase Clostridium histolyticum (CCH) injection for the treatment of Dupuytren’s contracture. We did not find any remarkable scarring around the Dupuytren’s cord and nodule three and a half years after the initial CCH injection. Pathological findings revealed the previously ruptured cord and partial continuity of the collagen tissue. If there is a sufficient duration between initial CCH injection and salvage surgery, fasciectomy can be performed without an adverse effect of the enzyme around the Dupuytren’s cord and nodule.

Author(s): Michiro Yamamoto, Takanobu Nishizuka, Hitoshi Hirata