Blattella germanica is commonly found in homes, restaurants, hospitals, other large buildings, and public health implications. It has become resistant to many insecticides. Latex effect of Euphorbia bupleuroides on B. germanica mortality was tested in order to obtain a new bioinsecticides. Five concentrations (0%, 25%, 50%, 75% and 100%) were evaluated against males, females and larvae of German cockroach under laboratory conditions. High levels of mortality of B. germanica adults and larvae were associated with the increase in the concentration and time of exposure as well.