The present study provides a baseline data on histology of respiratory system of Mizo local pig (Zo Vawk). The Occurrence of nasal glands was high in the respiratory region of nasal cavity which might enhance the efficiency of humidifying the inhaled air. The visceral pleura and interlobar and interlobular septa were thick containing elastic fibres which might increase the elasticity of the lung. The respiratory bronchioles were well developed in Mizo local pig which might enhance their respiratory efficiency in higher altitude and lesser atmospheric oxygen tension in Mizoram. Frequent occurrence of alveolar macrophages might be attributed to the better resistance to respiratory diseases of the indigenous pigs of Mizoram (Zo Vawk).