Biomedical Research

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Changes of BFGF and VEGF in patients with ischemic stroke treated by acupuncture-moxibustion with du channel-unblocking acupuncture method

Objective: This research is aimed to explore the changes of Basic Fibroblast Growth Factor (BFGF) and Vascular Endothelial Growth Factor (VEGF) before and after treatment with acupuncture-moxibustion with Du channel-unblocking acupuncture in patients with ischemic stroke.

Methods: In our hospital from Jan 2014 to Sep 2016, 240 cases of ischemic stroke patients were randomly divided into acupuncture-moxibustion with Du channel-unblocking acupuncture group (Group A) and routine acupuncture group (Group B) and treatment group (Group C). Group A was treated by acupuncture-moxibustion with Du channel-unblocking acupuncture therapy, Group B was treated with acupuncture therapy, and Group C was treated with routine drugs. Before and after treatment, the levels of BFGF and VEGF were compared between the three groups before and after treatment. The NIHSS score, MESSS score and ADL score were compared before and after treatment..

Results: Before treatment, the three groups of patients with BFGF, VEGF levels and NIHSS score, MESSS score, ADL score no statistical difference (P>0.05); After treatment, three groups of BFGF, VEGF levels and NIHSS score, MESSS score, ADL score than before treatment were improved (P<0.05); After treatment, the levels of BFGF, VEGF and NIHSS score, MESSS score, ADL score of Group A were higher than that of Group B and Group C (P<0.05).

Conclusion: The treatment of ischemic stroke patients with acupuncture-moxibustion with Du channelunblocking acupuncture therapy can improve the expression level of VEGF and BFGF, and also has a good effect on improving the clinical symptoms of patients.

Author(s): Huang WeiZhen, Yan Ming, Xie AiZe, Wang GuoZhen