Pediatric patients experience pain which is more difficult to assess and treat relatively to adults. Evidence demonstrates that controlling pain in the pediatrics age period is beneficial, improving physiologic, behavioral, and hormonal outcomes. Multiple validated scoring systems exist to assess pain in pediatrics; however, there is no standardized or universal approach for pain management. Healthcare facilities should establish pediatrics pain control program. This review summaries a collection of pain assessment tools and management practices in different facilities. This systematic approach should decrease pediatric pain and poor outcomes as well as improve provider and parent satisfaction.