Biomedical Research

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Research Article - Biomedical Research (2018) Volume 29, Issue 12

Antimicrobial sensitivity pattern of pathogenic bacteria isolated from older women with asymptomatic bacteriuria

Objectives: Asymptomatic bacteriuria is one of the most important silent diseases frequently infect women in worldwide.

Aims: To determine the antimicrobial susceptibility pattern of pathogenic bacteria isolated from older women with asymptomatic bacteriuria.

Materials and Methods: A total of 263 culture positive bacterial isolates from 862 urine samples were collected from older women (60-70 years old) admitted to Al-Najaf hospital in Al-Najaf Governorate, Iraq during January 2016 to December 2017. All bacterial isolates were identified according to standard microbiological tests. Antimicrobial susceptibility test was done according to method by Kirby-Bauer.

Results: Out of 263 culture positive urine samples, Escherichia coli was the most dominant bacterial isolates 109 (41.44%) followed by Klebsiella pneumoniae 85 (32.32%), Acinetobacter baumannii 32 (12.16%), Pseudomonas aeruginosa 18 (6.84%), Serratia marcescens 11 (4.18%) and Staphylococcus saprophyticus 8 (3.06%). Among all antimicrobials, Imipenem 10 μg showed the highest activity (100%) against E. coli, S. marcescens and S. saprophyticus isolates While, Amikacin 30 μg showed the highest activity (100%) against S. marcescens only. Most bacterial isolates 240 (91.3%) were multi-drug resistance (MDR), 16 isolates (6%) and 7 isolates (2.7%) were extensive drug-resistance (XDR) and pandrug- resistance (PDR), respectively.

Conclusions: There were many older women infected with asymptomatic bacteriuria caused by bacteria with high resistant to different antimicrobials; therefore, the antimicrobial sensitivity test must be done periodically.

Author(s): Ahmed Abduljabbar Jaloob Aljanaby, Israa Abduljabbar Jaloob Aljanaby

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