Biomedical Research

Journal Banner

A randomized double-blind controlled study on non-invasive ventilation in the treatment of children obstructive sleep with apnea syndrome (OSAS)

Objective: This research aimed to explore the curative effect of noninvasive ventilation in the treatment of children Obstructive Sleep Apnea Syndrome (OSAS).

Methods: From Nov 2015-2016, 70 children OSAS patients in Binzhou People’s Hospital were selected as the study subjects and were randomly divided into surgery group (n=35) and ventilation group (n=35). Patients in the surgery group were treated with routine operation while ventilation group were received non-invasive ventilation followed by the routine operation. The curative effects in the two groups were analyzed with statistical comparison method.

Results: Total effective rate of the ventilation group was significantly higher than that of the surgery group, partial pressure of carbon dioxide of the ventilation group was lower than that of the surgery group and the longest time of apnea, apnea hypopnea index as well as Epworth Sleepiness Score(ESS) of the ventilation group was obviously lower than that of the surgery group (P<0.05), while abortion and ectopic pregnancy rate of the intervention group was strikingly lower than that of the control group significantly.

Conclusion: Non-invasive ventilation has good effects in the treatment of children Obstructive Sleep Apnea Hypopnea Syndrome (OSHS).

Author(s): Baoqiang Li, Shuzheng Han, Qianqian Sun, Xiaohui Guo, Haitao Xie, Chuanwei Xu